Originally Posted by magic823
Based on how it works, I agree with him. It causes the nerves in your taste buds to fire. Sounds like drug to me.
That is a unique way to classify what is or is not a drug. MSG stimulates the taste perception Umami (the 5th taste sensation) through G-protein coupled receptors. So, if you are going to use that as the criteria for what is a drug there are a few problems since Sweet and Bitter are also tastes that are perceived through the GPCRs. Oh, Salty and Sour are perceived through ion channels.
MSG, sodium chloride (salt) and potassium chloride (used as a substitute for salt in sodium restricted diets) are use for their "flavor enhancing" properties.
But, they are also used as drugs ... MSG is added to IV solutions in treating some forms of encephalopathy (degeneration of brain function primarily secondary to advanced liver disease - hepatic encephalopathy) - and sodium and potassium chlorides are used in treading some cardiac problems - or any other electrolyte disturbances.
re some other posts:
I believe some people can be sensative to too much MSG - just like some people can't handle too large of a dose of capsaicin.
I do not know of any properties of MSG that would act as a meat tenderizing agent. The fact that Accent is located next to the meat tenderizers, like Adolph's meat tenderizer, doesn't mean any more than the fact that both are usually located with the salt, pepper, and other dried herbs and spices. My dad uses to use both Accent and Adolph/s on steaks - I doubt he would have done that if one would have accomplished both functions.