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Yes. However, if you can use ground chuck it would be better. With ordinary Ground beef (hamburger) you may have to use more than the 2 lbs. called for in the recipe, because a lot more fat will be cooked out leaving less meat. You will probably need to cook 2-3/4 pounds of ground beef to equal the same amound of boneless chuck roast, but only 2-1/4 pounds of ground chuck.
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