I've made meatloaf in my crock-pot many times. One thing you might want to do before you place the loaf into the crock-pot is to tear off two very long strips of foil. Make lengths of the strips equal to the measurement of the inside of the pot from the top edge to the bottom, from the bottom across to the other side and up that side. Fold the foil in quarters lengthwise and place them like a + in the bottom of the pot. Put your meatloaf in and cook.
When it's time to remove the meatloaf, lift it out with the foil "slings." This way you will get the meat out of the fat/juices that accumulate in the pot as it cooked. Let the meatloaf rest a few minutes before slicing. This should help.
"As a girl I had zero interest in the stove." - Julia Child
This is real inspiration. Look what Julia became!