sure, but you`ll have to reduce it quite a bit else it`ll be too "wet".
add some Garlic and Basil to this with a few bay leaves and oregano and leave it to simmer slowly until it goes like a paste.
you can also freeze it if you make too much
if it`s of any use to you for Future ref, I`v found that 3 pounds of tomatoes when cooked down and sieved of the skins and pips, then reduced down to Pizza sauce consistency (to my Own liking), is enough to do 2x 15" pizza bases.
I`m not sure how this compares with shop bought toms though as mine are homegrown as a rule.
V8 reductions are Very nice too, I use that for thick soups
also be very careful when you add salt! you can "hide" Massive amounts of salt in Tom sauces and hardly even notice it`s there, I`m not sure How it works, but don`t go by Taste for salting, if you Can taste it, there is probably a Dangerous amount in there.
Sugar is similar too with Tomatoes.
You can leave them as is and cook them that way. When the sauce is done, you can use a blender, sitck blender or food procesor to smooth it out. Pizza sauce is typically smooth.